Ilias Tachtsidis Selected Research

Electron Transport Complex IV (Cytochrome c Oxidase)

10/2019	Oxygen dependency of mitochondrial metabolism indicates outcome of newborn brain injury.
10/2019	Quantification of the severity of hypoxic-ischemic brain injury in a neonatal preclinical model using measurements of cytochrome-c-oxidase from a miniature broadband-near-infrared spectroscopy system.
1/2018	Broadband NIRS Cerebral Cytochrome-C-Oxidase Response to Anoxia Before and After Hypoxic-Ischaemic Injury in Piglets.
8/2017	Hyperoxia results in increased aerobic metabolism following acute brain injury.
1/2016	Interrelationship Between Broadband NIRS Measurements of Cerebral Cytochrome C Oxidase and Systemic Changes Indicates Injury Severity in Neonatal Encephalopathy.
1/2016	Changes in Cerebral Oxidative Metabolism during Neonatal Seizures Following Hypoxic-Ischemic Brain Injury.
1/2016	Near Infrared Light Scattering Changes Following Acute Brain Injury.
10/2014	A new broadband near-infrared spectroscopy system for in-vivo measurements of cerebral cytochrome-c-oxidase changes in neonatal brain injury.
1/2014	Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model.
1/2013	Dependence on NIRS source-detector spacing of cytochrome c oxidase response to hypoxia and hypercapnia in the adult brain.

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Ilias Tachtsidis Research Topics

Disease

12	Hypoxia (Hypoxemia) 01/2021 - 03/2007
10	Brain Diseases (Brain Disorder) 01/2022 - 01/2016
9	Brain Injuries (Brain Injury) 10/2019 - 01/2013
6	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2020 - 01/2016
5	Hypothermia 01/2020 - 03/2016
4	Ischemia 12/2019 - 01/2013
4	Hyperoxia 08/2017 - 01/2009
3	Inflammation (Inflammations) 01/2022 - 11/2016
2	Gliosis 01/2022 - 01/2019
2	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 11/2016
2	Asphyxia (Suffocation) 01/2017 - 03/2016
2	Hypercapnia 01/2014 - 01/2013
1	Ganglion Cysts (Ganglion) 01/2022
1	Wounds and Injuries (Trauma) 01/2020
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020
1	Demyelinating Diseases (Demyelinating Disease) 01/2020
1	Multiple Sclerosis 01/2020
1	Hypotension (Low Blood Pressure) 12/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2019
1	Neuroinflammatory Diseases 01/2019
1	Endotoxemia 11/2016
1	Cerebral Infarction 01/2016
1	Seizures (Absence Seizure) 01/2016
1	Low Cardiac Output 10/2014
1	Fever (Fevers) 10/2014
1	Hypocapnia 01/2014
1	Brain Hypoxia (Cerebral Hypoxia) 01/2014
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2011
1	Respiratory Insufficiency (Respiratory Failure) 01/2010
1	Orthostatic Hypotension (Postural Hypotension) 09/2006
1	Pure Autonomic Failure 01/2005

Drug/Important Bio-Agent (IBA)

15	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 10/2019 - 03/2007
8	Oxygen (Dioxygen)IBA 01/2020 - 09/2006
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2016
3	Lactic Acid (Lactate)FDA LinkGeneric 10/2019 - 03/2016
2	Caspase 3 (Caspase-3)IBA 01/2022 - 01/2019
2	Retinaldehyde (Retinal)IBA 01/2021 - 11/2016
2	Protons (Proton)IBA 10/2019 - 03/2016
2	N-acetylaspartate (N-acetyl aspartate)IBA 10/2019 - 03/2016
2	Adenosine Triphosphate (ATP)IBA 11/2016 - 03/2016
1	NeuroglobinIBA 01/2022
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2022
1	ChemokinesIBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2021
1	Complement Factor H (Factor H)IBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	CytokinesIBA 01/2021
1	SteroidsIBA 01/2020
1	mesoglycanIBA 01/2020
1	Nimodipine (Modus)FDA LinkGeneric 01/2020
1	MagnesiumIBA 12/2019
1	Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric 12/2019
1	LipopolysaccharidesIBA 01/2019
1	Pyruvic Acid (Pyruvate)IBA 08/2017
1	Dexmedetomidine FDA Link 01/2017
1	Hypnotics and Sedatives (Sedatives)IBA 01/2017
1	Fentanyl (Sublimaze)FDA LinkGeneric 01/2017
1	Dihydrotachysterol (AT 10)IBA 01/2017
1	Isoflurane FDA LinkGeneric 01/2017
1	SympatholyticsIBA 01/2017
1	Analgesics (Analgesic Drugs)IBA 01/2017
1	ArgonIBA 03/2016
1	Phosphorus (Red Phosphorus)IBA 03/2016
1	GasesIBA 01/2013
1	Hemoglobins (Hemoglobin)IBA 03/2007

Therapy/Procedure

8	Induced Hypothermia 01/2022 - 10/2014
4	Therapeutics 01/2020 - 01/2010
3	Rewarming 01/2020 - 01/2016
2	Extracorporeal Membrane Oxygenation 01/2013 - 01/2010
1	Ischemic Postconditioning 01/2016
1	Sympathectomy (Sympathectomies) 01/2005